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Original Articles

Development of Methods for Determination of Aflatoxins

, &
Pages 2642-2664 | Published online: 17 Aug 2016
 

ABSTRACT

Aflatoxins can cause damage to the health of humans and animals. Several institutions around the world have established regulations to limit the levels of aflatoxins in food, and numerous analytical methods have been extensively developed for aflatoxin determination. This review covers the currently used analytical methods for the determination of aflatoxins in different food matrices, which includes sampling and sample preparation, sample pretreatment methods including extraction methods and purification methods of aflatoxin extracts, separation and determination methods. Validation for analysis of aflatoxins and safety considerations and precautions when doing the experiments are also discussed.

Funding

We would like to gratefully acknowledge the financial support provided by the National Natural Science Foundation of China (No. 31471410).

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