Genomics of lactic acid bacteria: Current status and potential applications

Abstract

Lactic acid bacteria (LAB) are widely used for the production of a variety of foods and feed raw materials where they contribute to flavor and texture of the fermented products. In addition, specific LAB strains are considered as probiotic due to their health-promoting effects in consumers. Recently, the genome sequencing of LAB is booming and the increased amount of published genomics data brings unprecedented opportunity for us to reveal the important traits of LAB. This review describes the recent progress on LAB genomics and special emphasis is placed on understanding the industry-related physiological features based on genomics analysis. Moreover, strategies to engineer metabolic capacity and stress tolerance of LAB with improved industrial performance are also discussed.

Keywords:

• Fermented food
• genomics
• lactic acid bacteria
• metabolic engineering
• stress response

Disclosure statement

This work was financially supported by the National Natural Science Foundation of China (No. 31301546) and Fundamental Research Funds for the Central Universities (No. SCU2015D008).