Advanced search
Publication Cover
Journal of Essential Oil Research Volume 24, 2012 - Issue 6
Submit an article Journal homepage
195
Views
14
CrossRef citations to date
0
Altmetric
Articles

The essential oil of Mongolian Nepeta sibirica: a single component and its biological activities

Tsutomu Tsuruoka Laboratory of Microbiology, School of Pharmaceutical Sciences, Toho University, Miyama, Funabashi, Chiba, JapanCorrespondence[email protected]
,
Davaapurev Bekh-Ochir Laboratory of Microbiology, School of Pharmaceutical Sciences, Toho University, Miyama, Funabashi, Chiba, Japan
,
Fumio Kato Laboratory of Microbiology, School of Pharmaceutical Sciences, Toho University, Miyama, Funabashi, Chiba, Japan
,
Shatar Sanduin Institute of Chemistry & Chemical Technology of the Mongolian Academy of Sciences, Ulaanbaatar, Mongolia
,
Altantsetseg Shataryn Institute of Chemistry & Chemical Technology of the Mongolian Academy of Sciences, Ulaanbaatar, Mongolia
,
Amarjargal Ayurzana Laboratory of Organic Chemistry, Hovd University, Hovd, Mongolia
,
Tadaaki Satou Laboratory of Pharmacognosy, School of Pharceutical Sciences, Toho University, Miyama, Funabashi, Chiba, Japan
,
Wei Li Laboratory of Pharmacognosy, School of Pharceutical Sciences, Toho University, Miyama, Funabashi, Chiba, Japan
&
Kazuo Koike Laboratory of Pharmacognosy, School of Pharceutical Sciences, Toho University, Miyama, Funabashi, Chiba, Japan
 show all
Pages 555-559 | Published online: 05 Nov 2012
 
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Abstract

Nepeta sibirica L. has been used for the treatment of various diseases and is one of the traditional medicines of Mongolia. The essential oil of N. sibirica was shown to contain a single component by gas chromatography–mass spectrometry (GC–MS) analysis. The optical rotation and nuclear magnetic resonance (NMR) analyses demonstrated that the component was 4aα,7α,7aα-nepetalactone. This essential oil, that is, 4aα,7α,7aα-nepetalactone, showed antimicrobial activity against Staphylococcus aureus, Escherichia coli, Candida albicans and Aspergillus fumigatus. Cell cytotoxicity testing showed that the nepetalactone was cytotoxic to HL60 myeloma and Kato III stomach carcinoma cell lines. The essential oil of this Mongolian N. sibirica is useful for researching the bioactivity of nepetalactone, which has been difficult to prepare.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 380.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.