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Abstract
This study reports the chemical composition of the essential oil of Nashia inaguensis Millsp. organically cultivated in French Guiana. This essential oil was examined by a combination of GC/FID and GC-MS techniques. A total of thirty-one components accounting for 97% of the total GC/FID chromatogram were identified. The most abundant ones were carvacrol (23.1%), p-cymene (18.7%), γ-terpinene (14.6%), thymol methyl ether (10.3%), thymol (8.3%), trans-β-caryophyllene (8.0%) and myrcene (2.3%). The essential oil of N.inaguensis was tested for the first time for antifungal and antiparasitic activities against strains of several Candida spp. and Leishmania guyanensis respectively: the strong antimicrobial activity of this essential oil was confirmed in vitro by the definition of MIC values ranging from 125 μg/mL to 500 μg/mL according to the Candida species tested, while the anti-Leishmania activity assessed by the definition of an IC50 value seem negligible.
Acknowledgments
The authors are grateful to Guyarômes for the financial support they provided and for making the essential oil samples available.