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ABSTRACT
Citrus essential oils, thanks to their pleasant aroma, are certainly the most used ingredients in the formulation of hydroalcoholic fragrances. The non-volatile fraction of Citrus essential oil is composed for 10–20% of coumarins, furocoumarins and polymethoxyflavones. It is well known that furocoumarins induce photosensitization and have potential carcinogenic and mutagenic effects. It follows that furocoumarins levels in cosmetics product are constantly monitored by opinions and regulations issued by the International Fragrance Association.
The aim of this research article was to quantify coumarins, furocoumarins and polymethoxyflavones in thirty commercial hydroalcoholic fragrances using supercritical fluid chromatography in combination with triple quadrupole mass spectrometry technique (SFC-QqQ-MS). According to author’s knowledge, this is the first report on the determination of oxygen heterocyclic compounds in hydroalcoholic fragrances by means of SFC-QqQ-MS technique.
Acknowledgments
The authors thank Shimadzu and Merck Life Science corporations for the continuous support.
Disclosure statement
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
CRediT authorship contribution statement
Conceptualization: [Marina Russo]; Methodology: [Maria Rita Testa Camillo, Marina Russo]; Formal analysis and investigation: [Maria Rita Testa Camillo]; Writing – original draft preparation: [Marina Russo]; Writing – review and editing: [Marina Russo, Paola Dugo, Alessandra Trozzi]; Resources: [Luigi Mondello]; Supervision: [Luigi Mondello, Paola Dugo].
Supplementary Material
Supplemental data for this article can be accessed online at https://doi.org/10.1080/10412905.2023.2236626