TRIMETHYLCHLOROSILANE (TMCS) CATALYZED EFFICIENT REDUCTION OF SULFOXIDES TO THIOETHERS USING 3-MERCAPTOPROPIONIC ACID UNDER MILD REACTION CONDITIONS

Abstract

A variety of alkyl and aryl sulfoxides were successfully deoxygenated using 3-mercaptopropionic acid as reducing agent and a catalytic amount of trimethylchlorosilane (10–20 mol%) in CH₃CN at ambient temperature.

The authors thank the Institute for Advanced Studies in Basic Sciences and the Research Council for support of this work.

Notes

^a Isolated yields.