A MILD AND EFFICIENT CsOH-PROMOTED SYNTHESIS OF DITERTIARY PHOSPHINES

Abstract

A mild and efficient method for the synthesis of ditertiary phosphines has been developed. In the presence of cesium hydroxide, molecular sieves, and DMF, various dihalides were coupled with diphenylphosphine at room temperature, and the results have demonstrated that this methodology offers a general synthetic procedure producing a variety of ditertiary phosphines in high yields.

Keywords:

• Alkylation
• cesium hydroxide
• ditertiary phosphines
• ligand

Financial support from the National Science Foundation-Kentucky EPSCoR (596166) is gratefully acknowledged, as is support from Western Kentucky University. Also, we wish to thank Chemetall for their generous supply of cesium bases.

Notes

^a Refers to yield of isolated product.

^b All products were identified by comparison of their physical and spectroscopic data with those of authentic samples.