Abstract
Alkyllithium reacts with chlorophosphate to generate the α -lithio- alkylidenediphosphonate, which further reacts with halogen reagents to afford corresponding α -halogenated alkylidenediphosphonates.
We are greatful to the National Natural Science Fooundation of china (20172032) and Tsinghua University for Financial support.
Notes
a GC yields. Isolated yields are given in parentheses.