AN EFFICIENT SYNTHESIS OF POLYMETHYLENE-BIS-AROYL THIOUREA DERIVATIVES UNDER THE CONDITION OF PHASE-TRANSFER CATALYSIS

Abstract

Reaction of polymethylene diamine with aroyl chloride and ammonium thiocyanate under the condition of solid–liquid phase-transfer catalysis using polyethylene glycol-400 (PEG-400) as the catalyst yielded polymethylene-bis-aroyl thiourea derivatives 3a–q in good-to-excellent yield. The products have been characterized by analytical and spectral (IR and H¹ NMR) data.

Keywords:

• PEG-400
• Phase transfer catalysis
• polymethylene-bis-aroyl thiourea
• synthesis

Financial support of this work by the Natural Science Foundation of China (No. 20371040) and the Foundation (No. 02-18) of Northwest Normal University are acknowledged.

Notes

^a m.p. of 7 is 162–163°C (Lit.¹⁰ 163–164°C).

^b m.p. of 8 is 146–148°C (Lit.⁶148°C).