SIMPLE AND IMPROVED PREPARATION OF α-OXOPHOSPHONATE MONOLITHIUM SALTS

Abstract

Some α-OxoPhosphonate monolithium salts were synthesized by a facile one-step procedure. In this way, α-(2,4-dichlorophenoxyacetoxy)alkyl phosphonic acid dimethyl esters 5 can be transformed into the corresponding phosophonate monolithium salts 6 without influence on the carboxylic ester group under mild conditions.

Keywords:

• Phosphonate monolithium salt
• synthesis

We gratefully acknowledge financial support of this work by National Natural Science Foundation of China (Project No. 29572045, 20072008, 20372023) and National Key Basic Research Development Program of China (“973” Project No. 2003CB114400).