Abstract
A Horner-Wadsworth-Emmons reagent-ethyl 2-(diethylphosphono)propionate in the reaction with 2,2-disubstituted-1,3-cyclopentanediones, results in 4-oxohexanoic acid ethyl ester derivative up to 90% isolated yield. 31P-13C- and 1H-NMR study of the intermediates of the reaction involving the ethyl 2-(diethylphosphono)propionate was accomplished.
We would like to thank the Estonian Science Foundation for supporting the present work through Grant Numbers 5628, 5133, 4976 and also A.-M. Müürisepp for the mass spectra and T. Kailas for the infrared spectra of the coumpounds reported herein.