ArS-Mediated Ad_E Reaction of the Cobaltcarbonyl-Complexed Conjugated Enynes

Abstract

A novel approach to the synthesis of functionalized enynes is elaborated based on the protocol of the three-component coupling of arenesulfenyl chlorides, dicobalthexacarbonyl complexes of the conjugated enynes, and nucleophiles of the π-donor type and a possibility to employ the 1,6-enyne derivatives thus prepared as the substrates for the intramolecular Pauson–Khand cyclization is demonstrated.

Acknowledgments

We are indebted to Deutsche Forschungsgemeinschaft (Grant No. MA673/19) and to RFBR (Grants Nos. 03-03-32884 and 03-03-04001) for financial support of this work.