Abstract
Novel 4-(2-chloropyridin-4-yl)-N-aryl-1,3-thiazol-2-amines have been prepared by reacting (4-bromoacetyl)-2-chloropyridine with thiourea and substituted thioureas. The newly synthesized compounds have been characterized by analytical and spectral data. All the compounds have been screened for their antifungal and antibacterial activities. Almost all the compounds were found to possess excellent antifungal and antibacterial activities.
Acknowledgments
The authors thank the director, RSIC, Punjab University, Chandigarh; the head, Regional Sophisticated Instrumentation Centre (RSIC), Indian Institute of Technology (IIT), Chennai, for mass and NMR analysis; and the head, Sophisticate Analytical Instrumentation Facility (SAIF), Central Drug Research Institute (CDRI), Lucknow, for providing spectral data.