Simple and High Yielding Synthesis of New α-Aminophosphonates from Imines

Abstract

A simple and high yielding method was developed for the synthesis of novel α-aminophosphonates from imines, obtained from 2-chloroquinoline-3-carbaldehyde, by using triethylphosphite in the presence of chlorotrimethylsilane (TMSCl). This method developed for the synthesis of α -aminophosphonates gave excellent yields.

Keywords:

• 2-Chloroquinoline-3-carbaldehyde
• α-aminophosphonate
• imines
• TMSCl
• triethylphosphite

Acknowledgments

Authors are thankful to the Head, Department of Chemistry, Dr. B. A. M. University, Aurangabad for providing laboratory facilities and to A. Jadhav for providing spectral data.