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Phosphorus, Sulfur, and Silicon and the Related Elements Volume 183, 2008 - Issue 2-3
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Original Articles

High Throughput Screening Under Zinc-Database and Synthesis a Dialkylphosphinic Acid as a Potential Kari Inhibitor

Xing-Hai Liu The Research Institute of Elemento-Organic Chemistry, The State-Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, Nankai University, Tianjin, China
,
Pei-Quan Chen The Research Institute of Elemento-Organic Chemistry, The State-Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, Nankai University, Tianjin, China
,
Wan-Cheng Guo The Research Institute of Elemento-Organic Chemistry, The State-Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, Nankai University, Tianjin, China
,
Su-Hua Wang The Research Institute of Elemento-Organic Chemistry, The State-Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, Nankai University, Tianjin, China
&
Zheng-Ming Li The Research Institute of Elemento-Organic Chemistry, The State-Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, Nankai University, Tianjin, China
Pages 775-778 | Published online: 20 Jun 2008
 
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Abstract

A novel phosphorus derivative was synthesized through HTVS. The title compounds were confirmed by MS, 1H NMR, 31P NMR. The DOCK was also studied.

Acknowledgments

This work was funded by the National Basic Research Program of China (No. 2003CB114406), National Natural Science Foundation Key Project of China (No. 20432010), and The High Performance Computing Project of Tianjin Ministry of Science and Technology of China (No. 043185111-5).

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