Application of BU₄N⁺HSO₄⁻ as an Ionic Liquid and Acid Catalyst for Thioacetalization of Aldehydes and Ketones

Abstract

A variety of carbonyl containing compounds have been successfully reacted with 1,2-ethanedithiol in a thioacetylization reaction using tetrabutylammonium hydrogensulfate as a mild and efficient catalyst. Aldehydes and ketones react with good to excellent yields under mild conditions.

Keywords:

• Acid catalyst
• carbonyl compound
• ionic liquid
• thioacetalization

Acknowledgments

We gratefully acknowledge the funding support received for this project from the Isfahan University of Technology (IUT), I.R. Iran (A. R. H.), and Grants GM 033138, MH 065503, NS 033650 (A. E. R.) from the National Institutes of Health, USA. Further financial support from Center of Excellency in Chemistry Research (IUT) is gratefully acknowledged.