Abstract
2-Amino-(6-phenoxathiin-2-yl)-4-phenyl-nicotinonitrile has been synthesized and used as a starting material to construct a novel series of annulated and substituted pyrido[2,3-d]pyrimidine systems. Antibacterial and antifungal activities of some synthesized compounds were evaluated and reported.
Acknowledgments
All strains were kindly supplied from the Botany Department, Faculty of Science, Benha University, Egypt.
Notes
a Inhibition zone diameter d of either fungal growth or bacterial cells for each compound: +++ > 12 mm, highly active; ++ > 9 mm, moderately active; + > 7 mm, slightly active; − no inhibition observed.