A Green Protocol for Solvent-Free Conversion of Epoxides to Thiiranes with Dowex-50WX8–Supported Thiourea

Abstract

Structurally different epoxides were efficiently converted to the corresponding thiiranes by Dowex-50WX8–supported thiourea under solvent-free conditions. The reactions were carried out either in an oil bath or under microwave irradiation to give the thiiranes in 75–98% yields within 30 sec–120 min.

Keywords:

• Dowex-50WX8
• epoxide
• microwave
• solvent-free
• thiirane
• thiourea

We acknowledge the financial support of this work by the research council of Urmia University.

Notes

^a All reactions were carried out with 1 mmol of epoxide and Dowex-50WX8 (0.5 g) supported thiourea (3 mmol) at solvent-free conditions.

^b Temperature of oil bath was 60–70°C.

^c Microwave irradiation was carried out with 40% power amplitude (400 W).

^d Yields refer to isolated pure products.