A Simple, Microwave-Assisted, and Solvent-Free Synthesis of 2-Arylbenzothiazoles by Acetic Acid–Promoted Condensation of Aldehydes with 2-Aminothiophenol in Air

Abstract

An efficient and simple procedure has been developed for the synthesis of various 2-arylbenzothiazoles by acetic acid–promoted condensation of 2 -aminothiophenol with aromatic aldehydes under microwave irradiation and solvent-free conditions in high yields.

Keywords:

• Aldehydes
• 2-aminothiophenol
• 2-arylbenzothiazoles
• microwave irradiation

We wish to thank the Research Council of Bu-Ali Sina University, Hamedan, Iran, for financial support to carry out this research.

Notes

^aThe reaction times and yields under microwave irradaiation condition are shown in the parenthesis.

^bProducts were characterized by their physical properties, comparison with authentic samples, and by their spectral (¹H-NMR, ¹³C-NMR, IR) analysis.

^c Isolated yields.