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Original Articles

Silica-Supported LiHSO4 as a Highly Efficient, Mild, Heterogeneous, and Reusable Catalytic System for the Solvent-Free Synthesis of Bis(indolyl)methanes

, , , &
Pages 2508-2515 | Received 04 Jun 2008, Accepted 10 Sep 2008, Published online: 21 Sep 2009
 

Abstract

Silica-supported LiHSO4 (LiHSO4/SiO2) is used as a green, cheap, and efficient catalytic system for the synthesis of bis(indolyl)methanes via the condensation of indoles with carbonyl compounds under solvent-free conditions. The reactions proceed rapidly at room temperature, and the title compounds are obtained in high to excellent yields.

The authors thank Persian Gulf University and Payame Noor University Research Councils for financial support of this work.

Notes

a Isolated yield.

a Isolated yield.

a Isolated yield.

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