Regioselective Synthesis of Novel Functionalized Phosphanylidene Anthra[2,1-b]furan Derivatives Under Solvent-Free Conditions

Abstract

A convenient and efficient, regioselective, solvent-free procedure has been developed to react 2,6-dihydroxyanthraquinone, dialkyl acetylenedicarboxylates, and triphenylphosphine in one-pot, to afford novel phosphanylidene anthracenyl derivatives 3a-c, which at 90°C due to intramolecular nucleophilic attack formed novel phosphanylidene anthra[2,1-b]furans 4a–c in good yield.

Keywords:

• 2,6-Dihydroxyanthraquinone
• hydroxyfuran
• phosphanylidene anthracenyls
• triphenyl phosphine

Notes

*The concentrations for all compounds are 1.9 × 10 ⁻⁴ mol lit⁻¹.