Abstract
Benzyl DABCO bromide was found to be an efficient and mild reagent for the reduction of sulfoxides to the corresponding sulfide using sulfuric acid adsorbed silica gel under solvent-free conditions at room temperature.
Acknowledgments
We are thankful to the Damghan University of Basic Sciences for support of this work.
Notes
a Yield refers to isolated pure products.
b Sulfoxide/benzyl DABCO bromide/H2SO4-silica (1:2:4 mmol).
c The products were characterized from their spectral (IR and 1H NMR) and comparison to authentic samples.
a The reaction was carried out with 100 mol% of PhSiH3 and with 0.3 mol% of PMHS and 5mol% of MoO2Cl2.
b The reaction was carried out with 1.0 mmol of sulfoxide, 2 mmol of catecholborane, and 5 mol% of MoO2Cl2(H2O)2.
c The reaction was carried out with 1.0 mmol of sulfoxide, 2.0 mmol of BH3-THF, and 5 mol% of MoO2Cl2.
d The ratio of sulfoxide:1,3-dithiane:TABCO (2,4,4,6-tetrabromo-2,5-cyclohexadienone) is 1:1.1:0.2.