Rapid Synthesis and Biological Activities of Some New Benzothiazol-2-Ylhexahydro-S- Triazine Derivatives

Abstract

2,4,6-Substituted 1,3,5-tris(benzothiazolyl)hexahydro-1,3,5-triazine derivatives were synthesized by the condensation of substituted benzothiazoles with aldehydes by conventional as well as by microwave irradiation (solvent free and solid supported) methods. All compounds were tested for antibacterial and antifungal activities, and the results have been compared with standard drugs. Acaricidal and anti-feedant activities were also tested.

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Keywords:

• Acaricidal activity
• antifeedant activity
• antimicrobial activity
• benzothiazole
• solid support MW synthesis
• 1,3,5-triazine

Acknowledgments

We are thankful to CDRI, Lucknow, India, for the spectroscopic studies. We are also thankful to Dr. Ashish Bhatnagar, Head, Dept. of Microbiology, MDS University, Ajmer, India, for providing the antimicrobial screening facility.