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Original Articles

Three-Component Condensation of 2,4-Diaminoselenazole with Aldehydes and Meldrum’s Acid: Synthesis of 7-Aryl(alkyl)-Substituted 2-Amino-6,7-dihydro-4H-selenazolo[4,5-b]pyridin-5-ones

, , &
Pages 1230-1234 | Received 23 Nov 2008, Accepted 24 Nov 2008, Published online: 27 May 2010
 

Abstract

A method for the synthesis of 7-aryl(alkyl)-substituted 2-amino-6,7-dihydro-4H-selenazolo [4,5-b]pyridin-5-ones 5 based on three-component condensation of in situ–generated 2,4-diaminoselenazole 7 with aromatic (aliphatic) aldehydes 9 and Meldrum's acid 10 was developed.

Acknowledgments

Dedicated to Professor Naomichi Furukawa on the occasion of his 70th birthday.

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