A New and Efficient Procedure for the Production of 1,1-Diacetate from Corresponding Aldehydes Promoted by Silica Chromate (SiO₂-O-CrO₂-O-SiO₂)

Abstract

A wide range of aromatic aldehydes has been selectively converted to 1,1-diacetates using silica chromate (SiO₂‒O‒CrO₂‒O‒SiO₂) under solvent-free conditions at room temperature in moderate to good yields. This protocol is mild and efficient compared to other reported methods.

GRAPHICAL ABSTRACT

Keywords:

• Aldehydes
• 1,1-diacetates
• silica chromate
• solvent-free

Acknowledgements

Financial support for this work by the research facilities of Kashan University and Ilam University is gratefully acknowledged.

Notes

^aMolar ratio of reagents: aldehyde/acetic anhydride (1 mmol/1 mmol).

^bIsolated yield.

^aMolar ratio of reagents: aldehyde/acetic anhydride (1 mmol/1 mmol).

^bIsolated yield.

^aMolar ratio of reagents: aldehyde/silica chromate/acetic anhydride for entries 1–9, 11–15, and 17–20 (1 mmol/0.25 g/1 mmol); for entries 10 and 16 (1 mmol/0.25 g/2 mmol).

^bIsolated yield.