Simple and Efficient Synthesis of 1,3-Dithioles with Pyrimidinylidene or Pyrazolylidene Substituents

Abstract

2-Pyrimidinylidene-1,3-dithioles or 2-pyrazolylidene-1,3-dithioles are prepared by a three-component condensation reaction of pyrimidine-tetraone or 1H-pyrazole-4,5-dione, carbon disulfide, and dialkyl acetylendicarboxylates in the presence of tributylphosphine.

GRAPHICAL ABSTRACT

Keywords:

• 1
• 3-Dithiole
• acetylenic esters
• 1H-pyrazole-3
• 4-dione
• pyrimidine-2
• 4
• 5
• 6-tetraone

Notes

^aIsolated yields.