Synthesis and Herbicidal Activity of O,O-Dimethyl-(3-Phenacryloyloxy) Alkyl Phosphonates

Abstract

In an attempt to discover novel compounds with high biological activity and low toxicity, a series of new O,O-dimethyl-(3-phenacryloyloxy) alkyl phosphonates 4a–m have been designed and synthesized by the reaction of 3-phenacryloyl chloride with α-hydroxyalkyl phosphonate. All new compounds were characterized by elemental analysis, IR, and ¹H NMR spectroscopy as well as by mass spectrometry. The results of preliminary bioassay indicate that some of the target compounds have excellent inhibitory activities on Triticum aestivum (wheat) and Brassica napus L. (rape).

GRAPHICAL ABSTRACT

Keywords:

• O,O-Dimethyl-(3-phenacryloyloxy) alkyl phosphonates
• synthesis
• herbicidal activities

Acknowledgments

We gratefully acknowledge financial support of this work by the National Natural Science Foundation of China (Project No. 20862007) and Natural Science Foundation of Jiangxi Province (No. 2010GZH1399).