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Original Articles

One-Pot Stereoselective Synthesis of Dialkyl Phosphorylsuccinates from Phthalhydrazide, Activated Acetylenes, and Trialkyl(Aryl) Phosphites

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Pages 71-78 | Received 10 Feb 2010, Accepted 18 Mar 2011, Published online: 06 Dec 2011
 

Abstract

The multicomponent, one-pot reaction of dialkyl acetylenedicarboxylates with 2,3-dihydrophthalazine-1,4-dione in the presence of triphenyl phosphite or trialkyl phosphites leads to stable substituted phosphorylsuccinates in good yields.

GRAPHICAL ABSTRACT

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