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Phosphorus, Sulfur, and Silicon and the Related Elements Volume 187, 2012 - Issue 2
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Original Articles

Utility of Phthalimidoacyl Isothiocyanate in Synthesis of Quinazolines, Benzoxazoles, Benzimidazoles, 1,2,4-Triazoles, and Oxatriazepines

M. M. Hemdan Department of Chemistry, Faculty of Science, Ain Shams University, Abbasia, Cairo, Egypt
,
A. F. M. Fahmy Department of Chemistry, Faculty of Science, Ain Shams University, Abbasia, Cairo, Egypt
,
N. F. Aly Department of Chemistry, Faculty of Science, Ain Shams University, Abbasia, Cairo, Egypt
,
I. A. Hegazi Department of Chemistry, Faculty of Science, Ain Shams University, Abbasia, Cairo, Egypt
&
A. A. El-Sayed Department of Chemistry, Faculty of Science, Ain Shams University, Abbasia, Cairo, Egypt
Pages 181-189 | Received 19 Apr 2011, Accepted 14 Jun 2011, Published online: 05 Jan 2012
 
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Abstract

Phthalimidoacyl isothiocyanates 1a,b participated in a wide range of addition–cyclization reactions. Simultaneous or subsequent cyclization of the obtained adducts gave derivatives of quinazoline, benzoxazole, benzimidazole, 1,2,4-triazole, and oxatriazepine. The structures of all the products were confirmed by microanalytical and spectroscopic data.

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