Synthesis and Spectroscopic Evaluation of Novel N-, S-, and O-Substituted 1,4-Naphthoquinone Derivatives

Abstract

Novel O- S,O- S,S- N,N- and N,S-substituted naphthoquinone compounds were prepared by reaction of 2,3-dichloro-1,4-naphthoquinone and the corresponding nucleophiles in the presence of chloroform and triethylamine or ethanol solution of Na₂CO₃. The structures of the novel naphthoquinone compounds were characterized by micro analysis, FT-IR, UV/Vis, ¹H NMR, ¹³C NMR, MS, and fluorescence spectroscopy.

GRAPHICAL ABSTRACT

Keywords:

• 1,4-Naphthoquinones
• thioethers
• coumarin

Acknowledgements

The Authors thank the Research Fund of Istanbul University for financial support of this work.