Abstract
A simple, environmentally benign, and efficient method was developed for the preparation of 1,5-benzothiazepines via a one-pot condensation reaction of 2-aminothiophenol with 1,3-diaryl- 2-propenones using tetrabutylammonium tribromide as an efficient and versatile catalyst in water.
GRAPHICAL ABSTRACT
![](/cms/asset/81137647-3e36-4266-853d-fbed95e89fa1/gpss_a_627900_o_uf0001.gif)
Acknowledgments
We are pleased to acknowledge the financial support from Xinxiang Medical University.