Abstract
3H-Benzothiazole-2-thione and 3H-benzoxazole-2-thione were selectively S-alkylated by use of O-alkylisoureas as the alkylating reagents. The reactions could be performed under mild reaction conditions in short reaction times, and high yields were obtained using O-primary-alkylisoureas, whereas low yields were obtained with sec- and tert-alkylisoureas.
GRAPHICAL ABSTRACT
![](/cms/asset/21c1848a-f197-4727-97c4-7d6b3aa299bc/gpss_a_636229_o_uf0001.gif)
Acknowledgments
This work was supported by the National Natural Science Foundation of China (No. 20972020).