Solvent-Free Conditions as an Eco-Friendly Strategy for Synthesis of Organophosphorus Compounds

Abstract

A series of diverse NH- and CH-acids are used for a one-pot synthesis of stable phosphorus ylides and 1,4-diionic organophosphorus compounds by trapping of the zwitterionic intermediate from the reaction between triphenylphosphine and dialkyl acetylenedicarboxylates under solvent-free conditions. The structural geometry for one of the products was confirmed by single crystal X-ray diffraction analysis.

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GRAPHICAL ABSTRACT

Keywords:

• Solvent-free conditions
• acetylenic ester
• Ph₃P
• stable phosphorus ylides
• 1,4-diionic compounds

Acknowledgments

We gratefully acknowledge financial support from the Research Council of The University of Sistan and Baluchestan, Iran.