Abstract
A proline-based aminophosphinic acid ligand and it's vanadium complex have been synthesized and characterized by spectroscopic techniques. The inhibitory activity on pancreatic α-amylase and Baker's yeast α-glucosidase has been examined in vitro. The novel complex showed more inhibitory potency against pancreatic α-amylase and Baker's yeast α-glucosidase compared to acarbose as an antidiabetic drug.
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GRAPHICAL ABSTRACT
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Acknowledgments
The authors gratefully acknowledge support by the Institute for Advanced Studies in Basic Sciences (IASBS) Research Council under grant No. G2011IASBS120. The authors thank Dr. Mohammad Rafee, Institute for Advanced Studies in Basic Sciences (IASBS) for his help in cyclic voltammetry analysis.