Abstract
The addition of dialkyl H-phosphonates to isophthalaldimines 1a–d and pyridine-2,6-dicarboxaldimines 2a–d was investigated and led to the corresponding aminophosphonates. Diastereoselectivity of the addition to pyridine-2,6-dicarboxaldimines was lower than to isophthalaldimines. In contrast, addition of bis(trimethylsilyl) H-phosphonate to both groups of aldimines demonstrated that the diastereoselectivity in case of pyridine-2,6-dicarboxaldimines is comparable or even better than that for the isophthalic derivatives.
GRAPHICAL ABSTRACT
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Acknowledgments
Marek Dzięgielewski was the participant of the project entitled Doktoranci—Regionalna Inwestycja w Młodych naukowców—Akronim D-RIM, which is co-financed by the EU from the European Social Fund in the framework of the Operational Programme Human Capital, Priority VIII, Subaction 8.2.1. and is thankful for the scholarship.