Amberlyst-15 Catalyzed Synthesis of α′-Oxindole-α-Hydroxyphosphonates under Ultrasonic Irradiation

Abstract

An efficient and environment friendly protocol for the synthesis of α′-oxindole–α-hydroxyphosphonates by the condensation of substituted isatin and dialkylphosphite in the presence of amberlyst-15 is reported. This reaction gives good to excellent yields of products under heating and sonication conditions.

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GRAPHICAL ABSTRACT

Keywords:

• α′-oxindole-α-hydroxyphosphonates
• amberlyst-15
• sonication