A Simple Procedure to Ditertiary Phosphinocarboxylic Acids and Their Bisphosphine Oxides

Abstract

A simple two-step route to a series of carboxylic acid functionalized ditertiary phosphine oxides is described, including the X-ray crystal structures of three representative examples namely {Ph₂P(O)CH₂}₂N(CH₂)_nCO₂H (n = 3−5). Strong intermolecular O−H···O H-bonding is observed in all cases leading to distinct packing arrangements.

GRAPHICAL ABSTRACT

Keywords:

• Tertiary phosphine oxides
• ligands
• hydrogen bonding
• NMR spectroscopy
• X-ray crystallography

Acknowledgments

We would like to thank Loughborough University and The Leverhulme Trust (S.T.) for funding.