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Original Articles

Synthesis of 3-Fluoro-2-(Diethoxyphosphoryl) Imidazo[1,2-A]Pyrimidine

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Pages 1475-1477 | Received 14 Feb 2013, Accepted 17 Mar 2013, Published online: 20 Sep 2013
 

Abstract

The first representative of 3-fluoro-2-(dialkoxyphosphoryl)imidazo[1,2-a]pyrimidi nes has been synthesized by the reaction of N-(pyrimidin-2-yl)-2,2,2-trifluoroacetimidoyl chloride with triethyl phosphite.

[Supplemental materials are available for this article. Go to the publisher's online edition ofPhosphorus, Sulfur, and Silicon and the Related Elements to view the following free supplemental file: Figures]

GRAPHICAL ABSTRACT

Acknowledgments

This research was supported by the Russian Fond of Basic Research (Grants 11-03-00496-а, 11-03-00480-a, 12-03-00828-a) and program of Presidium of Russian Academy of Sciences “Development of the methodology of organic synthesis and creating of compounds with applied properties”.

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