Rice Husk Ash: A New, Cheap, Efficient, and Reusable Reagent for the Protection of Alcohols, Phenols, Amines, and Thiols

Abstract

A mild, efficient, and eco-friendly protocol for the protection of alcohols and phenols as trimethylsilyl ethers has been developed using rice husk ash as a reagent. This reagent is also able to catalyze the acetylation of alcohols, phenols, thiols, and amines with acetic anhydride. All reactions were performed under mild conditions in good to high yields.

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GRAPHICAL ABSTRACT

Keywords:

• Rice husk ash (RiHA)
• heterogenous reagent
• trimethylsilylation
• acetylation
• protection
• mild reaction conditions