GRAPHICAL ABSTRACT
Abstract
A series of biologically active phenoxy derivatives of 2-substituted benzoxazole organophosphates have been synthesized by the reaction of S-(benzoxazolyl-2)phosphorodichloridothioate/phosphorodichloridodithioate with phenol/4-chlorophenol/4-nitrophenol in 1:1 and 1:2 molar ratio. These compounds have been characterized by elemental analysis, IR, 1H NMR, and 31P NMR spectral studies. The antibacterial activity of these 2-substituted benzoxazolephenoxy derivatives has been evaluated against pathogenic bacteria Staphylococcus aureus (+ve) and Escherichia coli (–ve). The antifungal activity of these 2-substituted benzoxazolephenoxy derivatives has been evaluated against pathogenic fungi Aspergillusniger and Fusariumoxysporium. All the compounds were found to have moderate antibacterial and antifungal activity.
ACKNOWLEDGMENTS
The authors are thankful to the head of the Department of Chemistry, University of Rajasthan, Jaipur, India, for providing necessary facilities to carry out this research work.
FUNDING
Chandni Jain is grateful to the University Grant Commission, New Delhi, India, for financial support in the form of junior research fellowship vide grant number 09/149(0591)/2011 EMR-I.
SUPPLEMENTAL MATERIAL
Supplementary data for this article can be accessed on the publisher's website, www.tandfonline.com/gpss