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Original Articles

Synthesis and Biological Evaluation of a Phosphonate Phosphoantigen Prodrug

, , , , , , & show all
Pages 751-753 | Received 30 Aug 2014, Accepted 23 Sep 2014, Published online: 01 Jul 2015
 

GRAPHICAL ABSTRACT

Abstract

We have recently reported the synthesis of the first known phosphoantigen prodrug, and have demonstrated excellent gains in potency through delivery of the phosphoantigen to the intracellular domain of BTN3A1.

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