Abstract
Nucleophillic substitution reactions of 2,3-dichloro-1,4-naphthoquinone (1) were studied using a variety of piperidinol, piperidine, and piperazine derivatives. The N-substituted compounds were treated with some thiols and N,S-substituted compounds were formed. The structures of the new products were characterized by spectroscopic methods (1H NMR, 13C NMR, MS) and elemental analysis. The novel compounds were evaluated for their antibacterial and antifungal activity.