The Potential of Microwave in Organophosphorus Syntheses

GRAPHICAL ABSTRACT

Abstract

In this paper, our recent results in microwave (MW)-assisted organophosphorus chemistry have been summarized. First, the esterification and amidation of cyclic phosphinic acids are discussed to represent reactions that are practically impossible on conventional thermal heating. Then, our results on the alcoholysis of dialkyl phosphites are demonstrated to show reactions which are reluctant on simple heating, but proceed better on MW irradiation. This is followed by the alkylation of CH acidic compounds, where MW may substitute the phase transfer catalyst. It is also possible that MW and a phase transfer catalyst synergize each other. Finally, our recent findings on the P-ligand-free Hirao reaction under MW conditions are presented.

Keywords:

• Organophosphorus chemistry
• P-heterocycles
• microwave
• energetics
• catalysts