ABSTRACT
Reaction of N-isocyaniminotriphenylphosphorane with biacetyl in the presence of a carboxylic acid in water proceeds smoothly at RT (20–26°C) and neutral conditions to afford sterically congested 1,3,4-oxadiazole derivatives in high yields. The reaction proceeds smoothly and clearly under mild conditions and no side reactions were observed.
Funding
This work is funded by 2015 Yeungnam University Research Grant.