Functionalized 3H-1,2,3,4-triazaphosphole derivatives: Synthesis and structural characterization of novel low-coordinate phosphorus heterocycles

GRAPHICAL ABSTRACT

ABSTRACT

The synthesis of novel functionalized 3H-1,2,3,4-triazaphosphole derivatives is presented, making use of the modular [3+2] dipolar cycloaddition reaction between an azide and a phosphaalkyne. These low-coordinate phosphorus heterocycles were prepared in high yield and could be characterized crystallographically. This strategy provides the possibility to access hitherto unknown chelating and potentially chiral P^O ligands based on triazaphospholes.

KEYWORDS:

• Phosphorus heterocycles
• triazaphospholes
• P-ligands
• cycloaddition
• ligand design

Funding

The authors thank the Deutsche Forschungsgemeinschaft (DFG), the European Initial Training Network SusPhos (317404), and the Free University of Berlin, Institute of Chemistry and Biochemistry, for financial support.