ABSTRACT
Benzenethiol, as a reductive agent for the dehalogenation of various α-halocarbonyl compounds, is investigated in the K+/CH3CN system. The reaction affords the reduced compounds in high yields under mild reaction conditions, especially α-chlorocarbonyl compounds. Furthermore, the reaction performed under ultrasonic irradiation greatly shortens the reaction time.
Funding
This study was supported by the China 973 Program (grant No. 2003CB114406), the National Natural Science Foundation of China (grant No. 20772069 and 21102103), China Postdoctoral Science Foundation funded project (2014T70222).