ABSTRACT
A colorimetric and fluorescent cyanide probe bearing naphthol and sulfahydrazone groups has been designed and synthesized. This structurally simple probe displays a rapid response and high selectivity for cyanide in DMSO/EtOH (v/v = 2:8) solution. The addition of CN− to the sensor p-toluenesulfonyl-2-hydroxy-1-naphthylhydrazone (L3) induced a remarkable color change from pale-yellow to yellow, and green fluorescence changed to yellow. The 1H NMR titration and DFT calculations suggested that the selective sensing process is based on a nucleophilic addition reaction of cyanide to imine. Test strips based on sensor L3 were fabricated, which could act as a convenient and efficient test kit to detect CN− for “in-the-field” measurements.
Funding
This work was supported by the National Natural Science Foundation of China (Nos. 21262032, 21161018, and 21574104), the Program for Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China (No. IRT1177), the Natural Science Foundation of Gansu Province (No. 1010RJZA018), the Youth Foundation of Gansu Province (No. 2011GS04735) and NWNU-LKQN-11-32.