246
Views
4
CrossRef citations to date
0
Altmetric
Original Articles

Synthesis and characterization of (S)-BINOL-modified cyclotriphosphazene tetradentate ligands

, , , , &
Pages 1421-1424 | Received 08 Jul 2016, Accepted 08 Jul 2016, Published online: 18 Jul 2016
 

GRAPHICAL ABSTRACT

ABSTRACT

Three novel cyclotriphosphazene derivatives were synthesized by the reaction of hexachlorocyclotriphosphazene (HCCP) with (S)-BINOL and the potassium salt of 4-hydroxybenzaldehyde, and subsequent reduction of aldehyde groups to alcohol groups using sodium borohydride. The bromination reaction was carried out using PBr3 to give N3P3(O2C20H12)(OC6H4-p-CH2Br)4 (3). The target ligands were obtained by the reaction of compound 3 with morpholine, imidazole, and pyrazole, respectively. Structure of title compounds were characterized by 1H NMR, 13C NMR, 31P NMR, and ESI-MS. The Cu complex of 4 was effective in the cleavage of pUC19 DNA under physiological conditions.

Funding

This work was financially supported by the NSFC (no. 21572209), He'nan Scientific Committee (152102410018), and Foundation of He'nan Educational Committee.

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 2,235.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.