ABSTRACT
The microwave-assisted synthesis of mono- and bis(aminophosphine oxides) was studied using various secondary phosphine oxides as the P-reagent in condensation with paraformaldehyde and primary amines. After double deoxygenation, the bis-products were utilized as bidentate phosphine ligands in the synthesis of platinum complexes. α-Aryl-α-aminophosphine oxides and α-aryl-α-aminophosphonates were also prepared by the addition of >P(O)H species to imines.
Funding
The above project was supported by the Hungarian Scientific Research Fund (PD111895) and the Hungarian Research Development and Innovation Fund (K119202). Ádám Tajti is grateful for the financial support from the Gedeon Richter Talentum Foundation.