Novel multicomponent synthesis of 2-OXO-1, 2-diphenylethylidene hydrazinyl thiadiazinyl-2H-chromen-2-one derivatives

GRAPHICAL ABSTRACT

ABSTRACT

A series of novel 2-oxo-1,2-diphenylethylidene hydrazinyl thiadiazinyl-2H-chromen-2-ones (shown in Scheme 1) have been synthesized via multicomponent approach by the reaction of equimolar amount of benzil (1), thiocarobohydrazide (2), and substituted of 3-(2-bromoacetyl)-2H-chromen-2-ones (3a-i) in a shorter reaction time with good yields. All these compounds were characterized by their spectral and analytical data like IR, ¹H NMR, ¹³C NMR, and mass spectra.

KEYWORDS:

• 1, 3, 4-Thiadiazine
• benzil
• coumarin
• thiocarbohydrazide
• multicomponent reaction